In millions of surgical procedures on the gastro-intestinal (GI) system, surgical incisions are made and then closed with sutures and \ or staples. While sutures and staples are the standard of care for surgical wound closure, they are incapable of water-tight or air-tight sealing of wounds. Bowel content leakage from GI incisions is still one of the complications most dreaded by GI surgeons, due to its potential fatal implications.
In addition to and in correlation with the significant morbidity and mortality, GI anastomotic leaks are associated with a 56% increase in the length of stay and with an additional cost of $28,000 per patient on average.
Sealantis develops Seal-G, a Gastro-Intestinal (GI) bioresorbable sealant designed to prevent leakage of bowel content from GI suture- or staple-lines thereby preventing the morbidity and mortality associated with post-surgical leaks.